PERSIMMON TANNINS MAY WEAKEN COVID-19, JAPANESE SAVANTS SAY

Tannins from persimmon are effective at weakening the infection rate of coronavirus samples in saliva, according to the results of tests by a research group at Nara Medical University, in the western Japan city of Kashihara, on September 15, 2020, Honsu Kan reported for the Japanese edition of the Mainichi Shimbun.

Next, the university intends to proceed with clinical trials to prove whether the tannins' preventive ability remains when inside a human mouth and is also looking to recruit companies to help develop the findings into a product as soon as possible.

The group that confirmed the results is headed by Toshihiro Ito, a professor in immunology at the university, and Prof. Yano Hisakazu, who studies microbial infections. In their tests, they added a high concentration of persimmon tannins to a sample of human saliva with the new coronavirus in it. After 10 minutes, they then compared the sample with another where the tannins had not been introduced, and found that the virus's infectivity had reduced to one-ten thousandth or less of what it was before. At a news briefing, Prof. Ito said that while they have yet to be able to explain the mechanism that weakens the new coronavirus, they currently think the tannins attach to the virus's surface and prevent it from entering cells.

The research group did confirm in tests that the effects of the tannins are reduced if they are diluted. The tannins need to be in the mouth for a set amount of time if they are to begin suppressing the virus, and so it is currently envisaged that they could be used in products such as candies or gum.

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