Little-Known Virus That Cannot Be Prevented by Vaccines Surges Across the U.S.

A relatively unknown respiratory virus is spreading across the United States. Infections of human metapneumovirus (HMPV) have been rising since fall 2025.

HMPV presents with symptoms similar to the common cold, including cough, fever, runny nose, and wheezing.

The Centers for Disease Control and Prevention (CDC) reported that during the first week of March, the virus accounted for 5% of positive respiratory virus tests nationwide, Niti Majethia reported for Irish Star.

Wastewater surveillance data shows significant activity across multiple regions, raising concerns among public health officials.

Currently, there is no vaccine or specific antiviral treatment for HMPV.

The virus belongs to the same family as respiratory syncytial virus (RSV) and typically causes symptoms lasting about a week.

HMPV presents with symptoms similar to the common cold, including cough, fever, runny nose, and wheezing.

First identified in 2001, it spreads primarily through close contact with infected individuals. In the US, it follows a seasonal pattern, typically emerging in winter and lasting through spring.

For some individuals, symptoms can worsen into bronchitis or pneumonia. Infants and children under two, adults over 65, and those with weakened immune systems are at higher risk of severe illness.